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277 Peninsula Farm Road
Building 3, Suite “I” (Located within Inspire Wellness Center)
Arnold, MD 21012

More Complementary & Integrative Healthcare Articles
Histamine, MCAS, Allergies, and Lipedema: Why Complete Decongestive Therapy Matters

Lipedema is a complex condition characterized by painful, fibrotic fat accumulation, often mistaken for obesity or lymphedema. Many individuals with Lipedema also experience heightened histamine sensitivity and Mast Cell Activation Syndrome (MCAS), which contribute to chronic inflammation, swelling, and discomfort. These immune system responses can worsen Lipedema symptoms, leading to increased fluid retention, skin hypersensitivity, and difficulty tolerating compression therapy.
Managing these overlapping conditions requires a holistic approach—this is where working with a Certified Lymphedema Therapist (CLT) who is often a Physical or Occupational Therapist becomes essential. Through Complete Decongestive Therapy (CDT), individuals with Lipedema can significantly reduce swelling, pain, and inflammation. CDT includes manual lymphatic drainage (MLD) to promote lymph flow and toxin removal, compression therapy for fluid regulation, skincare to prevent infections, and targeted exercise to enhance circulation.
Additionally, CLTs can help individuals identify and manage histamine triggers, modify lifestyle factors, and incorporate supportive therapies like vibration plates and infrared light. Addressing the interplay between MCAS, histamine intolerance, and Lipedema through CDT empowers individuals to reduce swelling, regain mobility, reduce discomfort, and improve their overall quality of life. Seeking specialized care can be the key to managing symptoms effectively and preventing disease progression.
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